It's true, skeletons are a lot like humans, and spirits, and a whole host of other similar looking folks, aside from all the outer squishy trappings.

"And hair! But I try not to hold that against anybody," Papyrus offers, very generously.

But, that's probably not the stuff that Cole means. They had just been espousing values of others' well being, after all. Which makes sense to his impression of Cole so far, they'd started talking because there was some other person that Cole wanted to help be happy. But who was it, again?